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Baskets - Apparatus 1
Baskets - Apparatus 1
Basket Accessories
Basket Accessories
Basket Shaft
Basket Shaft
Basket Shaft Accessories
Basket Shaft Accessories
Baskets Small Volume
Baskets Small Volume
Biodissolution accessories - Apparatus 3
Biodissolution accessories - Apparatus 3
Calibration Tools
Calibration Tools
Cannula Filters
Cannula Filters
Capsule Sinkers
Capsule Sinkers
Disintegration Testing
Disintegration Testing
DissoGuard Systems
DissoGuard Systems
Dissolution Media Concentrates
Dissolution Media Concentrates
Filter Plates
Filter Plates
Fittings & Connectors
Fittings & Connectors
Flow Through - Apparatus 4
Flow Through - Apparatus 4
Intrinsic Dissolution
Intrinsic Dissolution
Paddles - Apparatus 2
Paddles - Apparatus 2
Paddle Accessories
Paddle Accessories
Paddles Small Volume
Paddles Small Volume
Pipettes
Pipettes
Sampling Cannulae
Sampling Cannulae
Service Parts
Service Parts
Spin Shafts
Spin Shafts
Syringes
Syringes
Syringe Filters
Syringe Filters
Tapped Density
Tapped Density
Tubing
Tubing
Paddle over Disk - Apparatus 5
Paddle over Disk - Apparatus 5
Rotating Cylinders - Apparatus 6
Rotating Cylinders - Apparatus 6
Vertical Diffusion Cells
Vertical Diffusion Cells
Transdermal Testing
Transdermal Testing
Vessels
Vessels
Vessel Accessories
Vessel Accessories
Vessel Backets / Rings
Vessel Backets / Rings
Vessel Covers
Vessel Covers
Vessels High Precision
Vessels High Precision
Vessel Small volume
Vessel Small volume
Volumetric Flasks
Volumetric Flasks
Waterbath Preservative
Waterbath Preservative
APPARATUS 1 - USP
The rotating basket apparatus consists of a cylindrical basket held by a shaft. The basket holds the sample and rotates in a round flask containing the dissolution medium. All Baskets are equivalent to the original OEM. All our baskets are laser marked with a unique serial number and come with a Certificate of Conformance.
Is there something you can't find, please feel free to contact us for custom work.
Agilent Compatible baskets
Caleva baskets
Distek baskets
Electrolab baskets
Erweka baskets
Hanson / Teledyne baskets
Logan baskets
Pharmatest baskets
Sotax baskets
Zymark baskets
Stationary Baskets
Stationary Felodipine Basket
Suppository baskets
Basket accessories
Dissolution accessories provides solutions for costumers all over the world. Whether it is about storing baskets, checking them against USP standards or attaching them to a basketshaft.
All Basket accessories
BASKET SHAFTS
The rotating basket assembly is individually serialized with the serial number laser imprinted on the shaft for record keeping purposes. These assemblies meet USP specifications requiring three retention spring clips for Apparatus 1 or o-ring push-on style. Shafts are standard electropolished, but also avaialble with different types of coatings.
Agilent Compatible basket shaft
Distek basket shaft
Electrolab basket shaft
Erweka basket shaft
Hanson / Teledyne basket shaft
Pharmatest basket shaft
Sotax basket shaft
Zymark basket shaft
Dabigatran Etexilate Mesylate (DEM)
Basket height spacers
Basket shaft holders
Agilent
Distek
Erweka
Hanson / Teledyne
APPARATUS 3 - USP
Biodissolution, also known as USP apparatus 3, is ideal for dissolution profiling of extended release dosage forms or any dosage form requiring release profiling at multiple pH levels. All parts are equivalents of the original OEM.
Caps & covers
Vessels & sampling tubes
Screens
CALIBRATION TOOLS
Qualification tools for performance verification testing and mechanical qualification for example (ASTM E2503-13). All of our tools are calibrated and USP/NIST traceable and can be used on multiple brands of dissolution testers.
ASTM / USP Qualification Tool Kit
Depth set tools
ASTM Qualification Tools
USP Prednisone Standards & Tablets
pH meter
Dissolved oxygen meter
Conductivity meter
(Re)Calibration service
CANNULA FILTERS
Filters are used on the end of a sampling cannula and feature a large surface area and optimized flow rate for an ideal choice in applications with a high presence of particulates. Filters are traceable by lot number and meet all current guidelines of USP and FDA.
Agilent Compatible cannula filters
Caleva cannula filters
Distek cannula filters
Electrolab cannula filters
Erweka cannula filters
Full Flow cannula filters
Hanson cannula filters
LabIndia cannula filters
Logan cannula filters
Pharmatest cannula filters
Sotax cannula filters
DISSOLUTION SINKERS
Floating dosage forms rarely dissolve at a reproducible rate. Using a sinker together with Apparatus 2 fixes the dosage form to a certain point and aids reproducibility. Sinkers can also be useful where dosage forms may stick to the sides of the vessel. Our sinkers can also be used in disintegration testing to prevent floating dosage forms.
Capsule size
Length
Diameter
(inches)
(mm)
(inches)
(mm)
000
1.029
26.1
0.390
9.91
00E
1.012
25.7
0.336
8.53
00
0.917
23.3
0.336
8.53
0E
0.909
23.1
0.301
7.65
0
0.854
21.7
0.301
7.65
1
0.765
19.4
0.272
6.91
2
0.709
18.0
0.250
6.35
3
0.626
15.9
0.229
5.83
4
0.563
14.3
0.209
5.32
5
0.437
11.1
0.193
4.91
Alf-(uzosin)/ Rop-(inirole) Hydrochloride cylinder sinker
Cage & basket sinkers
Metformin hydrochloride vertical holders
O-ring sinkers
Pronged sinkers
Sotax sinkers
Spiral sinkers
Stainless steel wire
Pouch
Time release capsule sinker
DISINTEGRATION TESTING
The current apparatus described in the Pharmacopoeias was designed to provide a reproducible and standardized method of ensuring that disintegration has taken place. Each of the tablets to be tested is placed in one of 6 vertical tubes arranged in a circular basket arrangement. The lower end of the tubes is covered by a sieve mesh. Other tubes sizes for larger tablets are also available.
Agilent Compatible disintegration accessories
Caleva disintegration accessories
Charles Ischi disintegration accessories
Copley disintegration accessories
Distek disintegration accessories
Electrolab disintegration accessories
Erweka disintegration accessories
Hanson disintegration accessories
Pharmatest disintegration accessories
Pharmatron/Secom disintegration accessories
Sotax disintegration accessories
ProSense disintegration accessories
DISSOGUARD SYSTEMS
With a unique design and powerful software the dissoGUARD® is a dissolution surveillance system that will revolutionize the way you see the dissolution procedure. With cameras placed underneath a dissolution bath the user is not only able to see and store real time videos, export pictures or complete videos for future analyses. For the first time, the user is able to measure or predict different physical parameters of their dissolution apparatus. With different algorithms the software can evaluate the wobble and measure RPM, determine the proper center alignment of individual shafts, and much more. Through the various stages of dissolution procedure it is possible to evaluate the proper position of dosage forms, timing and position of sampling cannulas, behavior of particles in vessels, etc.
DissoGuard
Conversion kits
Accessories
MEDIA CONCENTRATES
Dissolution Media Concentrates are consistant and cost effective to use. Dilute the concentrate by simply adding purified water, you will create “ready to use” dissolution media within a few minutes.
Media Preparator
Acetate buffer pH 4.5
Citrate buffer pH 4.8
Hydrochloric acid 0.01N
Hydrochloric acid 0.1N
Potassium Phosphate pH 4.5
Potassium Phosphate pH 5.8
Potassium Phosphate pH 6.0
Potassium Phosphate pH 6.5
Potassium Phosphate pH 6.8
Potassium Phosphate pH 7.2
Potassium Phosphate pH 7.4
Potassium Phosphate pH 7.5
Simulated Gastric Fluid (without enzyme)
Simulated Intestinal Fluid (without enzyme)
Sodium Lauryl Sulfate 0.50%
Sodium Phosphate pH 6.8
Cross Reference Whatman™ 850-DS 8-Channel Filter Plate to
Dissolution Accessories 850-DS 8-Channel Filter Plate
DA Part nr.
Description
OEM nr.
PSFPL-GF25-045-050
850-DS 8 Channel Filter Plate 0.45 µm GMF 50/pk
PSFPL-GF25-070-050
850-DS 8 Channel Filter Plate 0.7 µm GMF 50/pk
7707-3300
PSFPL-GF25-100-050
850-DS 8 Channel Filter Plate 1.0 μm GMF 50/pk
7707-3900
PSFPL-HP25-020-050
850-DS 8-Channel Filter Plate 0.2 µm PTFE 50/pk
7707-3400
PSFPL-HP25-045-050
850-DS 8-Channel Filter Plate 0.45 µm PTFE 50/pk
7707-3000
PSFPL-NY25-020-050
850-DS 8-Channel Filter Plate 0.2 µm Nylon 50/PK
7707-3500
PSFPL-NY25-045-050
850-DS 8-Channel Filter Plate 0.45 µm Nylon 50/pk
7707-3100
PSFPL-PS25-020-050
850-DS 8-Channel Filter Plate 0.2 µm PES 50/pk
7707-3600
PSFPL-PS25-045-050
850-DS 8-Channel Filter Plate 0.45 µm PES 50/pk
7707-3200
PSFPL-PV25-020-050
850-DS 8-Channel Filter Plate 0.2 μm PVDF 50/pk
7707-3700
PSFPL-PV25-045-050
850-DS 8-Channel Filter Plate 0.45 μm PVDF 50/PK
7707-3800
PVDF (PV)
Nylon (NY)
Glass Fiber (GF)
PTFE (HP)
PES Polyethersulfone (PS)
Barb Fittings
Luer fittings
Handbook of dissolution testing
Fittings
APPARATUS 4 - USP
The principal of this apparatus consists of a reservoir containing the dissolution medium, a pump that forces the medium upwards through the vertically positioned flow-cell, and a device to control the temperature in the cell.
USP 4 Flow through cells
USP 4 Cell holder
INTRINSIC DISSOLUTION - USP
The intrinsic dissolution rate is defined as the rate of dissolution of a pure pharmaceutical active ingredient when conditions such as surface area, agitation-stirring speed, pH and ionic-strength of the dissolution medium are kept constant. The determination of this parameter allows for screening of drug candidates and an understanding of there solution behaviour under different bio-physical conditions. All parts are equivalents of original OEM.
Intrinsic dissolution apparatus set
Intrinsic Shaft & holder
Intrinsic Surface plate with screws
Intrinsic die
Intrinsic Punch and handle
Intrinsic press
APPARATUS 2 - USP
The dosage form is dropped into the medium, which is stirred with a paddle attached to the stirring shaft. All paddles are equivalent to the original OEM.
Agilent Compatible paddles
Caleva paddles
Distek paddles
Electrolab paddles
Erweka paddles
Hanson paddles
Logan paddles
Pharmatest paddles
Sotax paddles
Paddle height spacers
Paddle holders
Agilent
Hanson / Teledyne
Distek
Electrolab
Erweka
Logan
Pharmatest
Sotax
Pipettes
Pipettes for easy, safe and precise sampling. We have pipettes in various volumes, suitable for any application. All pipettes are tested according to ISO 8655/DIN 12650
Single channel pipettes
Pipette accessories
CANNULAE
Sampling cannulae are used to take samples from the dissolution test and can be bend for easier accessibility to USP sampling position.
Agilent Compatible sampling cannula
Caleva sampling cannula
Distek sampling cannula
Electrolab sampling cannula
Erweka sampling cannula
Hanson sampling cannula
High capacity sampling cannula
Pharmatest sampling cannula
Sotax sampling cannula
Disposable sampling cannula
SERVICE PARTS
To keep dissolution instruments in optimum condition, a variety of equivalent parts are offered to service the OEM systems.
Agilent Compatible
Distek
Electrolab
Erweka
Hanson
Sotax
Zymark Multidose G3
SPIN SHAFT - USP
Interchangeable Paddle/Basket Shaft, also know as Spin On/Off shafts, allows the user to switch between paddles and basket shafts without height readjustment. The system is a two-piece assembly engineered to easily set the shaft length to maintain consistent clearance from the bottom of the vessel.
Agilent Compatible spin on/off shafts
Distek spin on/off shafts
Erweka spin on/off shafts
Hanson spin on/off shafts
Pharmatest spin on/off shafts
Glass syringes
Plastic Disposable syringes
Stainless Steel Syringes
Automation filters
Cellulose Acetate (CA)
Cellulose Nitrate (CN)
Glass Fiber (GF)
PTFE Hydrophilic (HP)
Nylon (NY)
PTFE Hydrophobic (PB)
Polypropylene Hydrophobic (PP)
Polyethersulfone (PS)
Polyester (PT)
PVDF (PV)
Regenerated Cellulose (RC)
TAPPED DENSITY - USP
Tapped density is achieved by mechanically tapping a volumetric cylinder containing a powder. The tapping is achieved by raising the cylinder and letting it drop under its own weight from a specific height. The mass increase is measured.
The Tapped Density Testers have been designed to measure the tapped density of powders, granules and similar products in accordance with
USP Chapter <616> Method 2 and European Pharmacopoeia Chapter 2.9.15.
Agilent Compatible tapped density funnels
Distek tapped density
Electrolab tapped density
Erweka tapped density
Sotax tapped density
Tubing is recommended for use with the Peristaltic Pump, syring pumps or any other fluidic path. Regular replacement of this tubing is recommended to prevent contamination. It is important to maintain the proper tubing lengths between components. Please visit our service part section for more specialised tubing between hardware components.
Aurosampler / Peristaltic pump tubing
PTFE tubing
Tygon tubing
The “Paddle over Disk” is a modified version of Method 2 (Paddle Method) and is used for the determination of the drug release rate of
transdermal patches
. It is described in the United States Pharmacopoeia (USP) under Chapter <724> as Method 5 and in the European Pharmacopoeia (Ph.Eur.) under Chapter 2.9.4. Method 1 as ‘Disk Assembly Method’.
Patch holders
Patch holder accessories
APPARATUS 6 - USP An alternative method for the testing of
transdermal patches
, USP Method 6 (Ph.Eur. Chapter 2.9.4. Method 3) employs the same dissolution equipment as Method 1 simply substituting a cylinder stirring element in place of the standard basket. The rotation speed normally employed is 100 rpm. The element is designed to accept various sizes of patches.
Agilent Compatible rotating cylinders
Copley rotating cylinders
Distek rotating cylinders
Electrolab rotating cylinders
Erweka rotating cylinders
Hanson rotating cylinders
Logan rotating cylinders
Pharmatest rotating cylinders
Sotax rotating cylinders
VERTICAL DIFFUSION CELL
.
Creams, ointments, lotions and gels are topical drugs normally described as semisolid dosage forms. Unlike transdermal drug systems (see Note) which are applied to the skin for systemic effects (the drug penetrates the skin whereupon it is then absorbed into the blood stream), topical drugs are applied to the skin for local action principally to counter dermatological problems. Current USP thinking suggests two types of test to characterise semisolids, product quality tests (USP Chapter <3>) and product performance tests (the proposed USP Chapter <1724>).
The Vertical Diffusion Cell or Franz Cell is a simple, reproducible test for measuring the drug release from creams, ointments and gels. It is rapidly emerging as the apparatus of choice for the in vitro testing of drug release of topical semisolid dosage forms. The cell comprises two parts (a) the sample holder containing either 250 mg or 425 mg of the sample to be tested and (b) the reservoir of the diffusion cell itself containing the receptor medium. The two parts are separated by a membrane designed to act as a conduit for diffusion to take place and which serves to contain the test sample whilst ensuring that it remains in contact with the receptor medium. The receptor temperature is usually set to 32 degrees C to approximate normal skin conditions. Normally, no fewer than 6 samples are taken over a 6 hour period, say, 0.5, 1, 2, 4, 5 and 6 hours and analysed using HPLC or similar analytical technique.
Manual Franz cell systems
Franz cell
Kerski cells
APPARATUS 5 - USP - USP - EP 2.9.4.
A variation to apparatus 2 with various methods as described in the USP and/or EP. The dosage form is applied to the apparatus and then placed at the bottom of the vessel.
PTFE suspension cups
Enhancer cell
Extraction cell
Immersion cells
Membranes
Vessels - USP <711>
Dissolution Accessories vessels are USP <711> and ASTM compliant. Vessel are serialized and will be supplied with a certificate of compliance. All DA manufactured vessels are compatible with the dimensional specifications of the OEM. This is important so the hydrodynamical propertities remain equivalent.
All vessels are available in PEAK, Amber or Teflon coated.
Please contact us for an inquiry
"Glass Rim" vessels
"Plastic Rim" vessels
"Magnetic Collar" vessels
Caleva vessels
Caliper/Zymark vessels
Copley vessels
Distek vessels
Electrolab vessels
Erweka vessels
Hanson / Teledyne vessels
Logan vessels
Pharmatest vessels
Sotax vessels
Toyama vessels
VESSEL ACCESSORIES
Vessel accessories designed to keep your vessels in excellent condition.
Vessel stands
Vessel protection rings
Centering brackets / Rings
These centering rings position the vessels accurately using diameter of the vessel. Empty vessels will not float. Locating pegs mounted on the vessel table ensure centering each time a vessel is placed in position. Our rings and brackets fit the original OEM.
Agilent Compatible vessel brackets/rings
Distek vessel brackets/rings
Erweka vessel brackets/rings
Hanson vessel brackets/rings
Logan vessel brackets/rings
Zymark vessel brackets/rings
COVERS
Evaporation covers slow the loss of media during dissolution testing. There are many types available, conical designs to return condensation into the vessel, low loss evaporation covers which dramatically reduces media loss during long runs, the two-piece hinged evaporation cover and covers with sample openings for cannulae.
Agilent Compatible vessel covers
Distek vessel covers
Hanson / Teledyne vessel covers
Pharmatest vessel covers
High Precision Vessels - USP
Highest specification vessels, with precise sphericity, circularity, concentricity of inner surface, vertical center and uniform geometry. Reduces variations in dissolution results and creates better conditions to pass the USP PVT (Performance Verification Test) at Stage 1.
Agilent Compatible high precision vessels
Copley high precision vessels
Distek high precision vessels
Electrolab high precision vessels
Erweka high precision vessels
Hanson / Teledyne high precision vessels
Logan high precision vessels
Pharmatest high precision vessels
Sotax high precision vessels
Toyama high precision vessels
Zymark high precision vessels
Caleva high precision vessels
SMALL VOLUME
A variation on apparatus 1 & 2 are available based on scaled down versions of the standard apparatus.
Small volume adapters
Small volume conversion kits
Agilent
Distek
Electrolab
Erweka
Hanson / Teledyne
Sotax
VOLUMETRIC GLASSWARE
Available as Tc / Td and according to ASTM- or USP standards.
Volumetric Flasks Tc/Td
Clear volumetric flasks ASTM/USP certified
Amber volumetric flasks ASTM/USP certified
Fleakers
ALGEACIDE
An algeacide stops the growth of algae, bacteria and other microorganisms with its bactericidal effectiveness. It protects the bath fluid and ensures a clean bath fluid.
AquaStabil
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Dissolution Media Concentrates
Dissolution Media Concentrates
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Dissolution Media Concentrates
Dissolution Media Concentrates
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All Dissolution Media Concentrates
MEDIA CONCENTRATES
Dissolution Media Concentrates are consistant and cost effective to use. Dilute the concentrate by simply adding purified water, you will create “ready to use” dissolution media within a few minutes.
Dissolution Media Preparation Station
PSMEDIADPREP
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