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APPARATUS 1 - USP <711>
The rotating basket apparatus consists of a cylindrical basket held by a shaft. The basket holds the sample and rotates in a round flask containing the dissolution medium. All Baskets are equivalent to the original OEM. Is there something you can't find, please feel free to contact us for custom work.

PSBSK040-01-USP-apparatus-I-1-basket-Agilent-40-mesh

Agilent Compatible baskets

Caleva baskets

PSBSK040-DK-USP-apparatus-I-1-basket-Distek-40-mesh

Distek baskets

Electrolab baskets

PSBSK020-EW-USP-apparatus-I-1-basket-Erweka-20-mesh

Erweka baskets

PSBSK100-HR-USP-apparatus-I-1-basket-Hanson-100-mesh

Hanson baskets

Logan baskets

PSBSK010-PTG-USP-apparatus-I-1-basket-gold-coated-Pharmatest-10-mesh

Pharmatest baskets

PSBSK040-ST-USP-apparatus-I-1-basket-Sotax-40-mesh

Sotax baskets

Zymark baskets

PSSTABSKF-01-USP-26-Felodipine-Stationary-basket-for-Agilent

Stationary baskets

PSBSKSUP-01-USP-apparatus-I-1-suppository-basket-plastic-Agilent

Suppository baskets

Basket accessories
Dissolution accessories provides solutions for costumers all over the world. Whether it is about storing baskets, checking them against USP standards or attaching them to a basketshaft.

All Basket accessories

BASKET SHAFTS
The rotating basket assembly is individually serialized with the serial number laser imprinted on the shaft for record keeping purposes. These assemblies meet USP specifications requiring three retention spring clips for Apparatus 1 or o-ring push-on style. Shafts are standard electropolished, but also avaialble with different types of coatings.

Agilent Compatible basket shaft

PSBSKSHT16-02-USP-apparatus-I-1-basket-shaft-Distek

Distek basket shaft

PSBSKSHT16-EL-USP-apparatus-I-1-basket-shaft-Electrolab

Electrolab basket shaft

PSBSKSHT16-EW-USP-apparatus-I-1-basket-shaft-Erweka

Erweka basket shaft

Hanson basket shaft

PSBSKSHT16-PT-USP-apparatus-I-1-basket-shaft-Pharmatest

Pharmatest basket shaft

PSBSKSHT-AT7-USP-apparatus-I-1-basket-shaft-Sotax

Sotax basket shaft

PSBSKSHT-ZM2-USP-apparatus-I-1-basket-shaft-conical-Zymark-Caliper

Zymark basket shaft

Basket height spacers

PSPADHLD-12A-Dissolution-Accessories-12-Position-Paddle-And-Basket-Shaft-Holder

Basket shaft holders

APPARATUS 3 - USP <711>
Biodissolution, also known as USP apparatus 3, is ideal for dissolution profiling of extended release dosage forms or any dosage form requiring release profiling at multiple pH levels. All parts are equivalents of the original OEM.

PSEVACOV-05-USP-Apparatus-III-3-PVC-Evaporation-Cover-Agilent

Caps & covers

PSGLA300-01-Clear-300-mL-USP-III-3-Apparatus-Vessel

Vessels & sampling tubes

Screens

CALIBRATION TOOLS
Qualification tools for performance verification testing and mechanical qualification for example (ASTM E2503-13). All of our tools are calibrated and USP traceable and can be used on multiple brands of dissolution testers.

PSASTMKT-Dissolution-accessories-ASTM-calibration-toolkit

ASTM / USP Validation tools

PSDEPGAG-DA-Dissolution-Accessories-ASTM-Digital-depth-gauge

Depth set tools

Measurement equipment

PSPRED-TAB-USP-Prednisone-Calibration-Tablets

USP Standards & tablets

pH meter kit

Dissolved oxygen meter kit

Conductivity meter kit

(Re)Calibration service

CANNULA FILTERS
Filters are used on the end of a sampling cannula and feature a large surface area and optimized flow rate for an ideal choice in applications with a high presence of particulates. Filters are traceable by lot number and meet all current guidelines of USP and FDA.

PSFIL001-01-1000-Dissolution-Accessories-Cannula-Filter-UHMW-Polyethylene-1-Micron-Agilent

Agilent Compatible cannula filters

PSFIL001-HR-100-Dissolution-Accessories-Cannula-Filter-UHMW-Polyethylene-1-Micron-Hanson

Caleva cannula filters

PSFIL010-DK-1000-Dissolution-Accessories-Cannula-Filter-UHMW-Polyethylene-10-Micron-Distek

Distek cannula filters

PSFIL001-FF-100-Dissolution-Accessories-Cannula-Filter-Full-Flow-UHMW-Polyethylene-1-Micron

Electrolab cannula filters

PSFIL001-HR-1000-Dissolution-Accessories-Cannula-Filter-UHMW-Polyethylene-1-Micron-Hanson

Erweka cannula filters

PSFIL001-FF-1000-Dissolution-Accessories-Cannula-Filter-Full-Flow-UHMW-Polyethylene-1-Micron

Full Flow cannula filters

Hanson cannula filters

Logan cannula filters

Pharmatest cannula filters

Sotax cannula filters

DISSOLUTION SINKERS
Floating dosage forms rarely dissolve at a reproducible rate. Using a sinker together with Apparatus 2 fixes the dosage form to a certain point and aids reproducibility. Sinkers can also be useful where dosage forms may stick to the sides of the vessel. Our sinkers can also be used in disintegration testing to prevent floating dosage forms.

Alf-(uzosin)/ Rop-(inirole) Hydrochloride cylinder sinker

PSBSK008-01-Dissolution-Accessories-basket-sinker

Cage & basket sinkers

Metformin hydrochloride vertical holders

Stainless steel wire

DISINTEGRATION TESTING
The current apparatus described in the Pharmacopoeias was designed to provide a reproducible and standardized method of ensuring that disintegration has taken place. Each of the tablets to be tested is placed in one of 6 vertical tubes arranged in a circular basket arrangement. The lower end of the tubes is covered by a sieve mesh. Other tubes sizes for larger tablets are also available.

Agilent Compatible disintegration accessories

Caleva disintegration accessories

Charles Ischi disintegration accessories

Copley disintegration accessories

Distek disintegration accessories

Electrolab disintegration accessories

Erweka disintegration accessories

Hanson disintegration accessories

Pharmatest disintegration accessories

Pharmatron/Secom disintegration accessories

Sotax disintegration accessories

MEDIA CONCENTRATES <711>
Dissolution Media Concentrates are consistant and cost effective to use. Dilute the concentrate by simply adding purified water, you will create “ready to use” dissolution media within a few minutes.

Media Preparator

Acetate buffer pH 4.5

Citrate buffer pH 4.8

Hydrochloric acid 0.01N

Hydrochloric acid 0.1N

Potassium Phosphate pH 4.5

Potassium Phosphate pH 5.8

Potassium Phosphate pH 6.0

Potassium Phosphate pH 6.5

Potassium Phosphate pH 6.8

Potassium Phosphate pH 7.2

Potassium Phosphate pH 7.4

Potassium Phosphate pH 7.5

Simulated Gastric Fluid (without enzyme)

Simulated Intestinal Fluid (without enzyme)

Sodium Lauryl Sulfate 0.50%

Sodium Phosphate pH 6.8

DISSOGUARD SYSTEMS
With a unique design and powerful software the dissoGUARD® is a dissolution surveillance system that will revolutionize the way you see the dissolution procedure. With cameras placed underneath a dissolution bath the user is not only able to see and store real time videos, export pictures or complete videos for future analyses. For the first time, the user is able to measure or predict different physical parameters of their dissolution apparatus. With different algorithms the software can evaluate the wobble and measure RPM, determine the proper center alignment of individual shafts, and much more. Through the various stages of dissolution procedure it is possible to evaluate the proper position of dosage forms, timing and position of sampling cannulas, behavior of particles in vessels, etc.

Handbook of dissolution testing

INTRINSIC DISSOLUTION - USP <1087>
The intrinsic dissolution rate is defined as the rate of dissolution of a pure pharmaceutical active ingredient when conditions such as surface area, agitation-stirring speed, pH and ionic-strength of the dissolution medium are kept constant. The determination of this parameter allows for screening of drug candidates and an understanding of thier solution behaviour under different bio-physical conditions. All parts are equivalents of original OEM.

Intrinsic dissolution apparatus set

PSIDASNH-01-Shaft-and-Holder-Intrinsic-Dissolution-Agilent

Intrinsic Shaft & holder

PSIDAPLT-01-Surface-Plate-with-Screws-Intrinsic-Dissolution

Intrinsic Surface plate with screws

PSIDADIE-01-8-mm-Die-including-gasket-Intrinsic-Dissolution

Intrinsic die

PSIDAPCH-01-8-mm-Punch-and-Handle-Intrinsic-Dissolution

Intrinsic Punch and handle

Intrinsic press

APPARATUS 2 - USP <711>
The dosage form is dropped into the medium, which is stirred with a paddle attached to the stirring shaft. All paddles are equivalent to the original OEM.

PSEPD013-01-USP-Apparatus-II-2-Electropolished-Paddle-14-5-inch-Agilent

Agilent Compatible paddles

PSEPDCA-01-USP-Apparatus-II-2-Electropolished-Paddle-Caleva

Caleva paddles

PSEPD016-02-USP-Apparatus-II-2-Electropolished-Paddle-16-inch-Distek

Distek paddles

PSEPD016-EL-USP-Apparatus-II-2-Electropolished-Paddle-16-inch-Electrolab

Electrolab paddles

PSEPD016-EW-USP-Apparatus-II-2-Electropolished-Paddle-16-inch-Erweka

Erweka paddles

Hanson paddles

PSEPD016-DK-USP-Apparatus-II-2-Electropolished-Paddle-16-5-inch-Distek

Logan paddles

PSEPD016-PH-USP-Apparatus-II-2-Electropolished-Paddle-16-inch-Pharmatest

Pharmatest paddles

PSEPDPAD-AT7-USP-Apparatus-II-2-Electropolished-Paddle-for-AT7-Sotax

Sotax paddles

Paddle height spacers

Paddle holders

Pipettes
Pipettes for easy, safe and precise sampling. We have pipettes in various volumes, suitable for any application. All pipettes are tested according to ISO 8655/DIN 12650

Single channel pipettes

Pipette accessories

CANNULAE
Sampling cannulae are used to take samples from the dissolution test and can be bend for easier accessibility to USP sampling position.

Agilent Compatible sampling cannula

Caleva sampling cannula

Distek sampling cannula

Electrolab sampling cannula

Erweka sampling cannula

Hanson sampling cannula

High capacity sampling cannula

Pharmatest sampling cannula

Sotax sampling cannula

Disposable sampling cannula

SERVICE PARTS
To keep dissolution instruments in optimum condition, a variety of equivalent parts are offered to service the OEM systems.

Agilent Compatible

Zymark Multidose G3

SMALL VOLUME<711>
A variation on apparatus 1 & 2 are available based on scaled down versions of the standard apparatus.

PSGLA100-01-100-mL-Clear-EaseAlign-Small-Volume-Dissolution-Vessel-Agilent

Small volume vessels

Small volume adapters

PSKIT150-HRV-150-mL-Small-Volume-Kit-Hanson-Vision

Small volume conversion kits

PSMINEPD-HR-Small-Volume-Electropolished-Mini-Paddle-Spin-On-Off-Style-Hanson

Small volume paddles

PSMINBSK-40-Small-Volume-Mini-Basket-40-Mesh-Hanson

Small volume baskets

SPIN SHAFT - USP <711>
Interchangeable Paddle/Basket Shaft, also know as Spin On/Off shafts, allows the user to switch between paddles and basket shafts without height readjustment. The system is a two-piece assembly engineered to easily set the shaft length to maintain consistent clearance from the bottom of the vessel.

Agilent Compatible spin on/off shafts

Distek spin on/off shafts

Erweka spin on/off shafts

Hanson spin on/off shafts

Pharmatest spin on/off shafts

Glass syringes

Automation filters

PSDSC-CA25-045-0150-Dissolution-Accessories-Cellulose-Acetate-Syringe-Filter

Cellulose Acetate (CA)

PSDSC-CA25-080-0150-Dissolution-Accessories-Cellulose-Acetate-Syringe-Filter

Cellulose Nitrate (CN)

PSDSC-GF25-100-0150-Dissolution-Accessories-Glass-Fibre-Syringe-Filter

Glass Fiber (GF)

PSDSC-HP25-020-0150-Dissolution-Accessories-PTFE-Hydrophilic-Syringe-Filter

PTFE Hydrophilic (HP)

PSDSC-NY25-020-0150-Dissolution-Accessories-Nylon-Syringe-Filter

Nylon (NY)

PSDSC-PB25-045-0150-Dissolution-Accessories-PTFE-Hydrophobic-Syringe-Filter

PTFE Hydrophobic (PB)

PSDSC-PP25-045-0150-Dissolution-Accessories-Polypropylene-Hydrophobic-Syringe-Filter

Polypropylene Hydrophobic (PP)

PSDSC-PS25-020-0150-Dissolution-Accessories-Polyethersulfone-Syringe-Filter

Polyethersulfone (PS)

Polyester (PT)

PSDSC-PV25-010-0150-Dissolution-Accessories-PVDF-Syringe-Filter

PVDF (PV)

PSDSC-RC25-022-0150-Dissolution-Accessories-Regenerated-Cellulose-Syringe-Filter

Regenerated Cellulose (RC)

TAPPED DENSITY - USP<616>
Tapped density is achieved by mechanically tapping a volumetric cylinder containing a powder. The tapping is achieved by raising the cylinder and letting it drop under its own weight from a specific height. The mass increase is measured.

PSGLA100TP-01-Graduated-Funnel-Top-Cylinder-Agilent

Agilent Compatible tapped density funnels

PSGLA250FT-DK-250-mL-Graduated-Funnel-Top-Cylinder-Distek

Distek tapped density

PSGLA250ST-EL-250-mL-Graduated-Funnel-Top-Cylinder-Electrolab

Electrolab tapped density

PSGLA250FT-EW-250-mL-Graduated-Funnel-Top-Cylinder-Erweka

Erweka tapped density

PSGLA250ST-ST-250-mL-Graduated-Funnel-Top-Cylinder-Sotax

Sotax tapped density

Tubing is recommended for use with the Peristaltic Pump, syring pumps or any other fluidic path. Regular replacement of this tubing is recommended to prevent contamination. It is important to maintain the proper tubing lengths between components.
Please visit our service part section for more specialised tubing between hardware components.

Peristaltic pump tubing

PTFE tubing

Tygon tubing

APPARATUS 5 - USP<724> - USP<1724> - EP 2.9.4.
A variation to apparatus 2 with various methods as described in the USP and/or EP. The dosage form is applied to the apparatus and then placed at the bottom of the vessel.

PTFE suspension cups

APPARATUS 4 - USP <711>
The principal of this apparatus consists of a reservoir containing the dissolution medium, a pump that forces the medium upwards through the vertically positioned flow-cell, and a device to control the temperature in the cell.

PSAPP4FC-12S-Sotax-compatible-USP-apparatus-IV-4-flow-cell-12mm-acrylic

USP 4 Flow through cells

PSCELLHLD-APP4-Aluminum-cell-holder-for-USP-IV-4-apparatus

USP 4 Cell holder

Patch holders

Patch holder accessories

APPARATUS 6 - USP <724>
The Apparatus 6 Rotating Cylinder is used for testing Transdermal Patches in any standard Dissolution Test Station. The cylinder is available in 2 size, for small and large patches. All cylinders are made of 316 stainless steel, are electropolished and are serialized for identification/tractability purposes. All cylinders are equivalents of original OEMs. Is there something you can't find, please feel free to contact us for custom work.

Agilent Compatible rotating cylinders

Copley rotating cylinders

Distek rotating cylinders

Electrolab rotating cylinders

Erweka rotating cylinders

Hanson rotating cylinders

Logan rotating cylinders

Pharmatest rotating cylinders

PSAPPSIX-ST-USP-apparatus-VI-6-Rotating-Cylinder-short-for-sotax

Sotax rotating cylinders

VERTICAL DIFFUSION CELL- USP <1724>
For drug release studies on topical semi-solids. The VDC is a small volume cell with a donor chamber containing the dosage form, a membrane through which the drug permeates and a receptor chamber. Typically test are done at 32 degrees C to simulate skin conditions.

Manual Franz cell systems

Franz cell

Kerski cells

Vessels - USP <711>
Dissolution Accessories vessels are USP <711> and ASTM compliant. Vessel are serialized and will be supplied with a certificate of compliance. All DA manufactured vessels are compatible with the dimensional specifications of the OEM. This is important so the hydrodynamical propertities remain equivalent.
All vessels are available in PEAK, Amber or Teflon coated. Please contact us for an inquiry

Agilent Compatible "Glass Rim" vessels

PSGLA900-TA-1-Liter-Clear-TruAlign-Dissolution-Vessel-Agilent

Agilent Compatible "Plastic Rim" vessels

PSGLA900-VKC-1-Liter-Clear-Dissolution-Vessel-with-Collar-Agilent

Agilent Compatible "Magnetic Collar" vessels

Caleva vessels

Caliper/Zymark vessels

Copley vessels

Distek vessels

Electrolab vessels

Erweka vessels

Hanson vessels

Logan vessels

Pharmatest vessels

Sotax vessels

Toyama vessels

High Precision Vessels - USP <711>
Highest specification vessels, with precise sphericity, circularity, concentricity of inner surface, vertical center and uniform geometry. Reduces variations in dissolution results and creates better conditions to pass the USP PVT (Performance Verification Test) at Stage 1.

Agilent Compatible high precision vessels

Copley high precision vessels

Distek high precision vessels

Electrolab high precision vessels

Erweka high precision vessels

Hanson high precision vessels

Logan high precision vessels

Pharmatest high precision vessels

Sotax high precision vessels

Toyama high precision vessels

Zymark high precision vessels

PSHPGLA900-ACP-Liter-High-Precision-Amber-Dissolution-Accessories-Copley

Caleva high precision vessels

VESSEL ACCESSORIES
Vessel accessories designed to keep your vessels in excellent condition.

Vessel stands

PSPRORNG-ST-Protective-Reing-For-AT7-Vessel-Sotax

Vessel protection rings

Centering brackets / Rings
These centering rings position the vessels accurately using diameter of the vessel. Empty vessels will not float. Locating pegs mounted on the vessel table ensure centering each time a vessel is placed in position. Our rings and brackets fit the original OEM.

PSEZLBKT-01-Vessel-Centering-Bracket-Model-7000-7010-705-DS-Agilent

Agilent Compatible vessel brackets/rings

PSRING01-DK-Acculign-Centering-Ring-Distek

Distek vessel brackets/rings

PSCNTRNG-EW-Vessel-Centering-Ring-Erweka

Erweka vessel brackets/rings

PSCNTRNG-HR-Vessel-Centering-Ring-Hanson

Hanson vessel brackets/rings

Logan vessel brackets/rings

PSRETRNG-ZM-Multidose-Vessel-Retainer-Zymark

Zymark vessel brackets/rings

COVERS
Evaporation covers slow the loss of media during dissolution testing. There are many types available, conical designs to return condensation into the vessel, low loss evaporation covers which dramatically reduces media loss during long runs, the two-piece hinged evaporation cover and covers with sample openings for cannulae.

PSCOVERV-00-Low-evaporation-rotary-cover-Agilent

Agilent Compatible vessel covers

Distek vessel covers

Hanson vessel covers

Pharmatest vessel covers

VOLUMETRIC GLASSWARE
Available as Tc / Td and according to ASTM- or USP standards.

Volumetric flasks

Clear volumetric flasks ASTM/USP certified

Amber volumetric flasks ASTM/USP certified

PSFLEAK-300-Dissolution-Accessories-Glass-Fleaker-300-mL

Fleakers

ALGEACIDE
An algeacide stops the growth of algae, bacteria and other microorganisms with its bactericidal effectiveness. It protects the bath fluid and ensures a clean bath fluid.

AquaStabil

Baskets

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Product number	PSSTABSK-40
Compatible with	Agilent
OEM reference	12-2063
Material	316 Stainless Steel
Spring Clip	yes
Stationary	yes

Baskets

Baskets

Stationary basket assembly including 40 mesh basket

Contact

About Prosense

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